Absorption, Distribution, Metabolism and Excretion of PPP Toxicants

This training is aiming to give you the basic knowledge of absorption, distribution, metabolism and excretion (ADME) studies in the context of Regulation 1107/2009 and in relationship with other Guidance.

17.10.2022
Online Training | Die Akademie Fresenius GmbH
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OverviewProgrammeSpeakersVenuePrices & Services

Overview

This training is aiming to give you the basic knowledge of absorption, distribution, metabolism, and excretion (ADME) studies in the context of Regulation 1107/2009 and in relationship with other Guidance. In a compact format of an intensive morning and afternoon session you will understand the design and conduct of in vivo ADME studies and of biotransformation studies. Furthermore, you will interpret results, including the derivation of oral absorption value, in vivo ADME studies and biotransformation studies.

Learning Outcomes:

  • Learn how ADME studies fit within the framework of Regulation 1107/2009 and other regulations
  • Understand the design and conduct of key ADME studies
  • Interpretation of ADME data for regulatory submission
  • Use of ADME data to support other disciplines

Who should attend this training?

Professionals working in the fields of:

  • Toxicology
  • Ecotoxicology
  • Exposure assessment
  • Risk assessment
  • Registration
  • Regulatory & government affairs
  • Monitoring & computer modelling

Sectors that should take part:

  • Agrochemical industry
  • Professional associations
  • Consultancies

Picture Credit: © sabelskaya – AdobeStock

 

Programme

PLEASE NOTE: The indicated times refer to Central European Summer Time CEST.

For further time zones, please view here.



Monday, 10 October 2022 | 10:00 – 16:00
The Expert

Alex Gledhill, ERM, UK

9:45
Login Time
10:00
Welcome address by the organisers and introduction by the trainer
10:10
Introduction and overview of ADME studies in the context of Regulation 1107/2009 and relationship with other Guidance
  • Data requirements under Regulation 1107/2009
  • Interaction of ADME across other guidance associated with Regulation 1107/2009
  • Overview of data generation to meet requirements
11:10
Short break
11:20
Design and conduct of in vivo ADME studies
  • Single and multiple dose excretion balance
  • Tissue distribution/depletion
  • Pharmacokinetics
12:20
Questions and answers
12:30
Lunch break
13:30
Design and conduct of biotransformation studies
  • Comparative in vitro metabolism
  • Metabolite profiling
  • Metabolite extraction and identification in vivo/in vitro
11:10
Short break
14:40
Interpretation of results
  • Derivation of oral absorption value
  • In vivo ADME studies
  • Biotransformation studies
15:40
Questions and answers
16:00
End of the online training

Speakers

Name

Company

Gledhill

Alex Gledhill

ERM, UK

Alex Gledhill is a Principal Toxicologist at ERM Regulatory Services Ltd. in Harrogate, United Kingdom, within the ERM Crop Protection/Product Stewardship Team. Alex moved into Consultancy 10 years ago having worked at Syngenta Central Toxicology Laboratory for 20 years where she was involved in all areas of regulatory and investigatory ADME and PK work for a range of crop protection chemicals, drugs and general chemicals, including both in vitro and in vivo metabolism studies. Alex has authored a number of papers and posters on ADME topics and also leads in silico toxicology at ERM.

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Venue

Online Training
This training is going to be held online.
Your Hotline for technical questions:
Phone : +49 231 75896-50
Email: infoakademie-fresenius.de
www.akademie-fresenius.de

Prices & Services

Participation Fee: € 495.00 plus VAT.

The registration fee includes the following benefits:

  • Participation in the Online Event
  • Certificate of participation
  • Training documentation (available after the training via download from our website)

Representatives of an authority or a public university are therefore eligible for a reduced fee of € 395.00 plus VAT per person (please provide evidence). The reduced fee cannot be combined with other rebates.

Group Reductions
For joint bookings received from one company we grant a 15% discount from the third participant onwards.

Terms of Cancellation / Book without Risk
You can cancel your participation in our online events free of charge and without giving reasons in writing up to 1 week before the start of the event. In the case of later cancellations and non-login to the online event, no participation fees can be refunded.
In this case, however, you will receive access to the documentation after the event.
You can name a substitute participant free of charge at any time.

Sabine Mummenbrauer

Your Contact

Sabine Mummenbrauer
Inhalt und Konzeption

+49 231 75896-82
smummenbrauerakademie-fresenius.de

Sabine Mummenbrauer

Your Contact

Sabine Mummenbrauer
Inhalt und Konzeption

+49 231 75896-82
smummenbrauerakademie-fresenius.de

Sabine Mummenbrauer

Your Contact

Sabine Mummenbrauer
Inhalt und Konzeption

+49 231 75896-82
smummenbrauerakademie-fresenius.de

Danielle Sörries

Your Contact

Danielle Sörries
Organisation und Teilnehmermanagement

+49 231 75896-74
dsoerriesakademie-fresenius.de

Danielle Sörries

Your Contact

Danielle Sörries
Organisation und Teilnehmermanagement

+49 231 75896-74
dsoerriesakademie-fresenius.de

Display / Supplement

Present your Company at the Event.

You can personally present your products and services directly to your specified target group. We are happy to provide you with further information on our range of available options – from displaying company information at the reception counter to presenting your company with an exhibition stand.

We would be pleased to assist you personally:

Analisa Mills

Analisa Mills
Phone: +49 231 75896-77
amillsakademie-fresenius.de

Press Contact

We offer journalists and editors a platform where they can get in touch with the experts.

If you are the editor of a specialist publication and interested in a press pass or media partnership, please contact us well in advance. We are happy to advise you.


Please contact us:

Katharina Geraridis

Katharina Geraridis
Phone: +49 231 75896-67
presseakademie-fresenius.de