NAMs in Toxicological Assessments and Regulatory Perspective

Tamara Coja is a Biologist and has been working as a Senior Regulatory Toxicologist at the Austrian Agency for Health and Food Safety (AGES) in Vienna. Since 2007 she has been involved in toxicological evaluation of pesticides. Her special regulatory interest is in toxicity of metabolites in residues of plant and animal origin and in groundwater. Since 2018 she is a member of the EFSA PPR Panel and joined working groups. She is also a member of the BfR Committee for Pesticides and their Residues.

Bertrand Desprez is the Deputy Head of the Toxicological Evaluation Unit of Pesticides (UETIV) in the Regulated Products Evaluation Directorate (RPD) at ANSES.

Felix M. Kluxen is a Pharmacist and Certified Toxicologist and has been a Regulatory Toxicologist for ADAMA since 2016. His main interests are NAMs, statistics in toxicology and risk assessment. He is a member of several CropLife Europe teams and international project groups.

Iris Mangas is a Regulatory Toxicologist. She holds a Ph D in molecular toxicology. Since 2018, she is a Scientific Officer at EFSA. She is currently in charge of the Peer Review of Pesticides Risk Assessment and supports the developmental activities for improving EFSA Risk assessment methods in the area of developmental neurotoxicity and Endocrine Disruptor properties, including development of IATA case studies and AOPs.

Martin Paparella has studied food- and biotechnology as well as toxicology. Currently he is a Senior Researcher in the field of regulatory toxicology at the Institute of Medical Biochemistry of the Medical University of Innsbruck in Austria. Martin aims to bridge science with the regulation of chemicals and is contributing to the development and standardization of non-animal-methods based approaches for regulatory toxicology within several related expert working groups for the OECD and EFSA. Martin also contributes to European research projects such as the European Partnership for the Assessment of Risk from Chemicals (PARC) and the European Horizon 2020 project ALTERNATIVE and national activities like the Austrian Green Chemistry Platform.

Douglas C. Wolf graduated in 1981 from the University of Missouri with a Doctor of Veterinary Medicine degree (D.V.M.) and, after 6 years in clinical veterinary practice, attended Purdue University where, in 1991, he completed a residency in pathology and Ph.D. in Veterinary Pathology. Douglas was a staff scientist for 6 years at the Chemical Industry Institute of Toxicology (CIIT) where he studied chemical carcinogenesis. From 1997 until 2013 Douglas held various research and leadership positions with the U.S. Environmental Protection Agency, where he continued research in chemical carcinogenesis and molecular pathology. In 2013 he joined Syngenta Crop Protection and is currently a Senior Syngenta Fellow where he leads international efforts to advance the science of risk assessment focusing on crop protection chemicals. Douglas has authored or coauthored over 155 journal articles, book chapters, and technical reports and is a Fellow of the International Academy of Toxicologic Pathologists and the Academy of Toxicological Sciences.

Anna J. van der Zalm is an Advisor to PETA Science Consortium International. She received her MChem (Master’s degree) in Chemistry from the University of Oxford, and gained experience in regulatory affairs prior to joining the Consortium in 2018, where she now focuses on the development and implementation of reliable and relevant non-animal approaches.