Online Training "Absorption, Distribution, Metabolism and Excretion of PPP Toxicants"

17 Oct 2022, Online Training | Die Akademie Fresenius GmbH

Online Training "Absorption, Distribution, Metabolism and Excretion of PPP Toxicants"

Overview Programme Speakers Venue Prices & Services

Overview

Absorption, Distribution, Metabolism and Excretion of PPP Toxicants

This training is aiming to give you the basic knowledge of absorption, distribution, metabolism and excretion (ADME) studies in the context of Regulation 1107/2009 and in relationship with other Guidance. In a compact format of an intensive morning and afternoon session you will understand the design and conduct of in vivo ADME studies and of biotransformation studies. Furthermore you will interprete results, including the derivation of oral absorption value, in vivo ADME studies and biotransformation studies. 

 

Learning Outcomes:

  • Learn how ADME studies fit within the framework of Regulation 1107/2009 and other regulations
  • Understand the design and conduct of key ADME studies
  • Interpretation of ADME data for regulatory submission
  • Use of ADME data to support other disciplines

 

Who should attend this training?

Professionals working in the fields of:

  • Toxicology
  • Ecotoxicology
  • Exposure assessment
  • Risk assessment
  • Registration
  • Regulatory & government affairs
  • Monitoring & computer modelling

Sectors that should take part:

  • Agrochemical industry
  • Professional associations
  • Consultancies

 

Picture credit: ©sabelskaya – Adobe Stock

Programme

PLEASE NOTE: The indicated times refer to Central European Summer Time CEST.
For further time zones, please view here

 

The Expert: Alex Gledhill, ERM, UK

9:45 Login Time

10:00 Start of the Online Training

Welcome address by the organisers and introduction by the trainer

10:10 Introduction and overview of ADME studies in the context of Regulation 1107/2009 and relationship with other Guidance

  • Data requirements under Regulation 1107/2009
  • Interaction of ADME across other guidance associated with Regulation 1107/2009
  • Overview of data generation to meet requirements

11:10 Short break

11:20 Design and conduct of in vivo ADME studies 

  • Single and multiple dose excretion balance 
  • Tissue distribution/depletion
  • Pharmacokinetics

12:20 Questions and answers

12.30 Lunch break

13:30 Design and conduct of biotransformation studies 

  • Comparative in vitro metabolism
  • Metabolite profiling 
  • Metabolite extraction and identification in vivo/in vitro

14:30 Short break

14:40 Interpretation of results

  • Derivation of oral absorption value
  • In vivo ADME studies
  • Biotransformation studies

15:40 Questions and answers

16:00 End of the online training

Speakers

Name

Company

Gledhill

Alex Gledhill

ERM, UK

Alex Gledhill is a Principal Toxicologist at ERM Regulatory Services Ltd. in Harrogate, United Kingdom, within the ERM Crop Protection/Product Stewardship Team. Alex moved into Consultancy 10 years ago having worked at Syngenta Central Toxicology Laboratory for 20 years where she was involved in all areas of regulatory and investigatory ADME and PK work for a range of crop protection chemicals, drugs and general chemicals, including both in vitro and in vivo metabolism studies. Alex has authored a number of papers and posters on ADME topics and also leads in silico toxicology at ERM.

mehrweniger

Venue

Online Training | Die Akademie Fresenius GmbH
This training is going to be held online.
Your Hotline for technical questions:
Phone: +49 231 75896-50
E-Mail: infoakademie-fresenius.de
www.akademie-fresenius.de

Prices & Services

Participation Fee: € 495.00 plus VAT.

The registration fee includes the following benefits:

  • conference participation
  • certificate of participation

Representatives of an authority or a public university are therefore eligible for a reduced fee of € 295.00 plus VAT per person (please provide evidence). The reduced fee cannot be combined with other rebates.

Group reductions

For joint bookings received from one company, we grant a 15 % discount from the third participant onwards (it doesn’t apply for representatives of an authority or a public university).


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Sabine Mummenbrauer

Your Contact

Sabine Mummenbrauer
Programme and conceptual design

+49 231 75896-82
smummenbrauerakademie-fresenius.de

Sabine Mummenbrauer

Your Contact

Sabine Mummenbrauer
Programme and conceptual design

+49 231 75896-82
smummenbrauerakademie-fresenius.de

Sabine Mummenbrauer

Your Contact

Sabine Mummenbrauer
Programme and conceptual design

+49 231 75896-82
smummenbrauerakademie-fresenius.de

Danielle Sörries

Your Contact

Danielle Sörries
Organisation and participant management

+49 231 75896-74
dsoerriesakademie-fresenius.de

Danielle Sörries

Your Contact

Danielle Sörries
Organisation and participant management

+49 231 75896-74
dsoerriesakademie-fresenius.de

Display / Supplement

Present your company at the event.

You can personally present your products and services directly to your specific target group. We would be happy to provide you with further information (without further obligation) on our range of available options – from displaying company information at the reception counter to including a supplement with information on your product portfolio in the event documentation package.

We would be pleased to assist you personally:

Analisa Mills

Analisa Mills
Phone: +49 231 75896-77
amillsakademie-fresenius.de

Press contact

We offer journalists and editors a platform where they can get in touch with the experts.

If you are the editor of a specialist publication and interested in a press pass or media partnership, please contact us well in advance. We would be pleased to send you our press bulletin as well as photographic materials where available as soon as the event is over.

Please contact us:

Katharina Geraridis

Katharina Geraridis
Phone: +49 231 75896-67
presseakademie-fresenius.de